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Measure OMR with minimal experimenter effort

Optomotor response (OMR) is a reflex used to assess vision in mice. In order to evoke OMR, a mouse watches a rotating cylinder with a striped pattern. Stimulus correlated head movements are quantified to determine visual thresholds. The qOMR (quantitative OMR) is a unique system that automatically measures OMR with minimal experimenter effort. It uses a virtual stimulation sphere that constantly aligns with the animal´s head position. Based on real-time head tracking quantitative OMR measurements run fully automatically and objectively.


Quantitative optomotor response (OMR) features & benefits

  • Simple, robust, and non-invasive test to examine vision in rodents
  • Fully automated measurement and analysis: no manual positioning of the stimulus, no specially trained experimenter required, time and cost effective, and unbiased
  • As a reflex, OMR measurements do not require animal training
  • Freely behaving animals, no surgery, no fixation
  • Flexible, user-friendly experimental design and data handling.
  • Calibrated 4 screen environment for presenting the virtual stimulation sphere
  • Elevated central platform for placing the unrestrained animal
  • Top and bottom mirror to create an illusion of infinite depth
  • IR-camera with adjustable IR-illumination for automated head tracking.

qOMR applications

1. Investigation of various aspects of vision in mice and other rodents

  • Visual acuity
  • Contrast sensitivity
  • Spectral sensitivity
  • Temporal sensitivity

2. Characterisation or preclinical testing in relevant disease models, for example

  • Glaucoma
  • Retinal degeneration
  • Diabetes
  • Aging

3. Examination of axonal regeneration

 


qOMR compatible products

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